HBsAgGi:
HB surface antigen glycan isomer
A monoclonal antibody to O-glycosylated PreS2 on M-HBs, which is predominantly expressed by DNA-containing viral particle.
Materials included in the kit
Applicable Genotype: C 50μg
Western
Immunoprecipitation/Separation of HBV particles
ELISA
HBV infection inhibition assay
Immunohistochemistryr
Isotype: mouse IgG1
Light chain: kappa
Amount: 50 μg
Storage: Store at –20℃ and avoid freeze / thaw cycle. Aliquots should be frozen and thawed once, with any remainder kept at 4℃ for short period.
mouse IgG1 kit Features
| Item | Description |
|---|---|
| Overview | HBV envelope protein is composed of three types of surface antigens, S-, M-, and L-HBs, which are produced from an HBsAg gene containing PreS1, PreS2 and S-domains1. HBsAgs are heavily glycosylated with N-glycan and O-glycan2,3. Whole glycan structural analyses revealed that PreS2 domain on M-HBs, but not on L-HBs, contains highly conserved O-glycosylated site in genotype C (gC)4,5. |
| Unit | 50μg |
| Cost | US$700.00- |
| Product Code: | RCA-001 |
| Applicable Genotype: | Genotype: C |
| How to order | This product can be purchased directly from us |
| Distributor | Our products can be purchased from the following distributor. FUJIFILM Wako Pure Chemical Corporation |
| Leaflet | Leaflet  |
| Safety data sheet | Safety data sheet [JP] Safety data sheet [EN] |
| User Guide | User Guide |
| References: | 1. Schadler and Hildt (2009) Viruses 1:185-209. 2. Schmitt et al. (2004) J Gen Virol 85:2045-2053. 3. Dobrica et al. (2020) Cells 9:1404. 4. Wagatsuma et al. (2018) Anal Chem 90:10196-10203. 5. Angata et al. (2021) Biochim Biophys Acta Gen Subj. 1866:130020 |