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\"\"<\/figure>\n\n\n\n

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\"\"<\/figure>\n\n\n\n
<\/div>\n\n\n\n

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\n
\u7814\u7a76\u7528\u8a66\u85ac\u30da\u30fc\u30b8<\/a><\/div>\n\n\n\n
\u53d7\u8a17\u30b5\u30fc\u30d3\u30b9\u30da\u30fc\u30b8<\/a><\/div>\n<\/div>\n\n\n\n
<\/div>\n\n\n\n
\u53c2\u8003\u6587\u732e:<\/strong>
1. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b<\/a>
2. Schadler and Hildt (2009) Viruses 1:185-209. doi: 10.3390\/v1020185.
3. Schmitt et al. (2004) J Gen Virol 85:2045-2053. doi: 10.1099\/vir.0.79932-0.
4. Dobrica et al. (2020) Cells 9:1404. doi: 10.3390\/cells9061404.
5. Wagatsuma et al. (2018) Anal Chem 90:10196-10203. doi: 10.1021\/acs.analchem.8b01030
6. Angata et al. (2021) Biochim Biophys Acta Gen Subj. In Press. doi:10.1016\/j.bbagen.2021.130020
7. Wang et al. (2016) J Hepatol. 65:700-710. doi: 10.1016\/j.jhep.2016.05.029.<\/pre>\n\n\n\n
<\/div>\n\n\n\n
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\"\"<\/figure>\n\n\n\n
<\/div>\n\n\n\n
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\u7279\u306bN\u578b\u7cd6\u9396\u4fee\u98fe\uff08N-\u30b0\u30ea\u30b3\u30b7\u30eb\u5316\uff09\u306f\u3001\u305d\u306e\u9ad8\u5ea6\u306b\u5206\u5c90\u3057\u305f\u69cb\u9020\u306b\u7531\u6765\u3057\u3066\u3001\u65e2\u5b58\u306e\u6297\u4f53\u533b\u85ac\u54c1\u306e\u7d50\u5408\u3092\u59a8\u3052\u3066\u3001\u305d\u306e\u85ac\u7406\u4f5c\u7528\u3092\u6e1b\u5f31\u3055\u305b\u305f\u308a\u3001\u4f53\u5185\u306e\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u304b\u3089\u9003\u308c\u308b\u201cImmune evasion\u201d\u306e\u539f\u56e0\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n
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\u5f53\u793e\u3067\u306f\u3001 \u201cGlea\u2122 platform\u201d\u3092\u6d3b\u7528\u3057\u3066\u3001\u304a\u5ba2\u69d8\u304c\u95a2\u5fc3\u3092\u6301\u3064N-\u30b0\u30ea\u30b3\u30b7\u30eb\u5316\u6a19\u7684\u306b\u5bfe\u3059\u308b\u6297\u4f53\u3092\u4f5c\u88fd\u3059\u308b\u30b5\u30fc\u30d3\u30b9\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n
\n\n\n
\u6297\u4f53\u4f5c\u6210\u30b5\u30fc\u30d3\u30b9\u30da\u30fc\u30b8<\/a><\/div>\n<\/div>\n\n\n\n
<\/div>\n\n\n\n
\u7814\u7a76\u958b\u767a\u62c5\u5f53\uff1a\u5c71\u7530 \u6d0b\u4ecb\uff08\u7814\u7a76\u958b\u767a\u90e8\u9577\uff09<\/strong><\/strong><\/h3>\n\n\n\n
\u30002012\u5e74\u3000\u3000\u5343\u8449\u5927\u5b66\u3000\u533b\u5b66\u85ac\u5b66\u5e9c\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\uff08\u85ac\u5b66\u535a\u58eb\uff09
\u30002012\u5e74\uff5e\u3000\u5927\u6b63\u88fd\u85ac\u682a\u5f0f\u4f1a\u793e\u5165\u793e\uff08\u5275\u85ac\u5316\u5b66\u7814\u7a76\u5ba4\u3001\u5275\u85ac\u6280\u8853\u7814\u7a76\u5ba4\uff09
\u30002017\u5e74\u3000\u3000\u7c73\u56fdVanderbilt\u5927\u5b66\u7559\u5b66
\u30002021\u5e74\uff5e\u3000\u682a\u5f0f\u4f1a\u793e\u30ad\u30e5\u30e9\u30a4\u30aa\u5165\u793e\uff08\u5275\u85ac\u5316\u5b66\u7814\u7a76\u5ba4\u9577\uff09
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\u30002024\u5e74\uff5e\u3000\u73fe\u8077<\/p>\n\n\n\n
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  • \u3053\u308c\u307e\u3067\u306b\u56fd\u5185\u88fd\u85ac\u4f01\u696d\u306b\u3066\u7d0410\u5e74\u304a\u3088\u3073\u56fd\u5185\u30d0\u30a4\u30aa\u30d9\u30f3\u30c1\u30e3\u30fc\u306b\u3066\u7d043\u5e74\u306e\u533b\u85ac\u54c1\u7814\u7a76\u958b\u767a\u306e\u7d4c\u9a13\u3092\u6709\u3057\u3001\u611f\u67d3\u75c7\u9818\u57df\u3092\u542b\u3080\u8907\u6570\u306e\u5275\u85ac\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3092\u30ea\u30fc\u30c9\u3002<\/li>\n\n\n\n
  • \u5275\u85ac\u30b9\u30c6\u30fc\u30b8\u3068\u3057\u3066\u306f\u521d\u671f\u306e\u63a2\u7d22\u6bb5\u968e\u304b\u3089\u958b\u767a\u5316\u5408\u7269\u540c\u5b9a\u3001\u304a\u3088\u3073\u305d\u306e\u5f8c\u306e\u524d\u81e8\u5e8a\u8a66\u9a13\u6bb5\u968e\u306e\u7d4c\u9a13\u3092\u6709\u3057\u3001\u7269\u8cea\u7279\u8a31\u304a\u3088\u3073\u88fd\u6cd5\u7279\u8a31\u7b49\u306e\u53d6\u5f97\u5b9f\u7e3e\u304c\u3042\u308b\u3002<\/li>\n\n\n\n
  • \u82f1\u56fd\u304a\u3088\u3073\u4ecf\u56fd\u306e\u4f01\u696d\u3068\u306e\u5171\u540c\u7814\u7a76\u3082\u4e3b\u5c0e\u3057\u6210\u529f\u306b\u5c0e\u304f\u306a\u3069\u3001\u5275\u85ac\u9818\u57df\u3067\u306e\u5b9f\u7e3e\u3092\u6709\u3059\u308b\u3002<\/li>\n<\/ul>\n\n\n\n
    \u4e3b\u8981\u8ad6\u6587\u30fb\u7279\u8a31:<\/strong>
    \u30fbBioorganic & Medicinal Chemistry Letters, 29, (2019), 2670-2674
    \u30fbJournal of Medicinal Chemistry, 63, (2020), 14805-14820
    \u30fbBioorganic & Medicinal Chemistry Letters, 50, (2021), 128342
    \u30fbAntiviral Research, 234, (2025), 106077
    \u30fbWO2014\/199960
    \u30fbJP2016\/199499
    \u30fbWO2018\/216822
    \u30fbWO2018\/216823<\/pre>\n\n\n\n
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